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KMID : 0043319920150020134
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Archives of Pharmacal Research
1992 Volume.15 No. 2 p.134 ~ p.137
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Inhibitory Effect of Papaverine on the Contraction Induced by Transmural Stimulation in the Isolated Mouse Vas Deferens
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Park EH
Song YS
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Abstract
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The effect of papaverine on the contractions induced by adrenergic neurotransmission in the isolated mouse vas deferens was investigated. Papaverine, 10-7 - 10-5M, showed a dose-dependent and reversible inhibition on the induced contractions. When the frequency of stmulation was varied (2.5-20.0 Hz), the inhibitory effect tended to be marked at the lower frequencies.
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